The 81st Annual Meeting of the American Association of Physical Anthropologists (2012)


Genome-wide markers and the peopling of South America

CECIL M. LEWIS1, MATTIAS JAKOBSSON2 and RAUL Y. TITO1.

1Anthropology, University of Oklahoma, U.S.A., 2Evolutionary Biology, Evolutionary Biology Centre, Uppsala University, Sweden

Friday 3:45-4:00, Grand Ballroom II Add to calendar

Initial inferences of the peopling of South America from molecular genetic data were dependent on a handful of classical genetic markers and/or markers with uniparental inheritance (mitochondrial and Y chromosome). These studies supported a clear picture for the peopling of South America from single North American gene pool, and this picture has remained robust by subsequent molecular studies. However, the characterization of hundreds of independently evolving loci, such as that provided by genome-wide marker studies, provided an unprecedented level of information for modeling and inferring the last great continental expansion of our species. In this presentation, we present the current state of genomics and its contribution inferring the number and path of the initial migrations into the Americas as well as the impact of subsequent population dynamics, including global admixture.

The Lewis lab is supported by grants from the U.S. National Science Foundation (#0845314) and the U.S. National Institutes of Health (GM089886-01A1 and HG005172-01).

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