The 81st Annual Meeting of the American Association of Physical Anthropologists (2012)

Shape analysis of the palpebral fissure in humans


Anthropology, University of Freiburg

Saturday All day, Plaza Level Add to calendar

The shape of the palpebral fissure is relevant to medical research for various reasons. It may, for example, indicate Down syndrome (Trisomy 21) or fetal alcohol syndrome (FAS). For diagnostic purposes, it is common to measure the length of the palpebral fissure or to qualitatively describe its shape. Existing studies mainly involve images of persons with opened eyes.

This study evaluates a new approach to quantify palpebral fissure shape using the concept of crestlines and statistical shape analysis. By applying these methods, observer error is minimized because the crest line algorithm automatically detects points of highest curvature in a certain surface area while statistical shape analysis allows for a comprehensive interpretation of those configurations. 200 CT scans of Asian and European male and female individuals with closed eyes were used to determine whether there are significant shape differences depending on age, sex, and population affinity.

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